The oldest known continuous congregation in the River Region is Cain’s Chapel in Holtville. The first church was a log church built by Elisha Milton Cain almost as soon as he moved his family from South Carolina to the territory that would later become the State of Alabama. The chapel was used for Cain, his family and the men and women who worked for him.  

The log church was built on Cain property in Pine Flat where a few of the old logs still reside; however, the Presbyterian Church of Pine Flat now occupies that territory. Surprisingly, Cain and his family are not buried in the cemetery at the current Cain’s Chapel, but all are buried in Mt. Zion Cemetery, the first cemetery for the log church location.Â